Comments on: An Overworked Powerhouse: A Boolean Model of Mitochondrial Dysfunction Associated Senescence in the Context of Aging Microglia /2023/04/14/katie-flieg/ Mon, 15 May 2023 15:39:25 +0000 hourly 1 https://wordpress.org/?v=6.9.4 By: Katie Fleig /2023/04/14/katie-flieg/#comment-29986 Fri, 21 Apr 2023 20:35:11 +0000 /?p=41251#comment-29986 Hi Miss Odya!! I’m so glad you checked out my work!

1. True!!
2. I know!! I just thought it would help remind people about where they’ve heard the name “mitochondria” before!!
3. Yes, they are free radicals, and to my knowledge they are still called that, ROS is just a more specific names for the oxygen-containing free radicals produced by the electron transport chain to support the hydrogen gradient.
4. So for this model, the difference is the “_H” modifier in the name of the node, but biologically from my understanding it’s essentially the point at which the DNA damage response isn’t favorable compared to apoptosis. Needless to say, it’s a bit arbitrary and is dependent upon whatever is happening in the cell. That’s my understanding and best guess!
5. It’s a tradition at Vlogý where whenever you turn in your thesis, you get a tootsie roll, and they made giant blow up ones for people to take pictures with!

I would have loved to have you here, countless questions or not! I’m just happy you saw the webpage and had questions and comments! I am more than happy to answer all the questions you can think of, just email me and I’ll answer! Thank you so much for stopping by!

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By: Erin Odya /2023/04/14/katie-flieg/#comment-29925 Fri, 21 Apr 2023 17:06:39 +0000 /?p=41251#comment-29925 1. I’m pretty sure it’s not possible to be too interested in how our brains can malfunction!
2. I can’t believe you said the mitochondria are powerhouse of the cell! Grrrr
3. Are ROS just free radicals? Are they even called that anymore?
4. What’s the difference between moderate and high amounts of damage?
5. Why are you holding a giant tootsie roll?

I wish I could be there for this. Though you’re probably glad I’m not! I’m quite proud of you and wouldn’t actually bombard you with questions anyway. And I’m totally kidding about #2. Kinda. Ok, not at all. LOL

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By: Katie Fleig /2023/04/14/katie-flieg/#comment-29910 Fri, 21 Apr 2023 16:38:27 +0000 /?p=41251#comment-29910 Thanks, Allison! I can’t wait to see your poster!

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By: Allison Ringold /2023/04/14/katie-flieg/#comment-29878 Fri, 21 Apr 2023 15:40:00 +0000 /?p=41251#comment-29878 This looks so cool! Looking forward to seeing your presentation!!

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By: Katie Fleig /2023/04/14/katie-flieg/#comment-29737 Thu, 20 Apr 2023 23:46:16 +0000 /?p=41251#comment-29737 Thanks guys!! Thank you for all your support!!

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By: Mrs. Lesley Karpiuk /2023/04/14/katie-flieg/#comment-29728 Thu, 20 Apr 2023 22:17:01 +0000 /?p=41251#comment-29728 Oh my goodness, Katie! Congratulations on this outstanding accomplishment! You never cease to amaze me, and I’m so thankful you’ve kept in touch. So proud of you!
Mrs. Karpiuk

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By: Ellen Fleig /2023/04/14/katie-flieg/#comment-29726 Thu, 20 Apr 2023 22:11:21 +0000 /?p=41251#comment-29726 👏👏!!! Mom, Dad and Jackson]]> Congratulations on your amazing accomplishment Katie!! We are so proud of you👏👏👏!!!
Mom, Dad and Jackson

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